Methyl 6-aminonicotinate - Names and Identifiers
Methyl 6-aminonicotinate - Physico-chemical Properties
Molecular Formula | C7H8N2O2
|
Molar Mass | 152.15 |
Density | 1.238±0.06 g/cm3(Predicted) |
Melting Point | 158-162 °C (lit.) |
Boling Point | 304.5±22.0 °C(Predicted) |
Flash Point | 137.9°C |
Solubility | DMSO, Methanol |
Vapor Presure | 0.000872mmHg at 25°C |
Appearance | White-like solid |
Color | White to light yellow-beige or pink |
pKa | 4.78±0.13(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
MDL | MFCD00797844 |
Methyl 6-aminonicotinate - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
|
UN IDs | 2811 |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
Methyl 6-aminonicotinate - Introduction
Methyl 6-aminonicotinate(Methyl 6-aminonicotinate) is an organic compound with the chemical formula C8H9NO2. It is a white crystalline solid with a nicotine-like odor.
Methyl 6-aminonicotinate has a variety of uses in the pharmaceutical and chemical industries. As a derivative of a compound, it can be used to synthesize other organic compounds, such as pharmaceutical raw materials in medicine or active ingredients in pesticides. In addition, Methyl 6-aminonicotinate can also be used as a food additive to improve the taste and aroma of food.
One way to make Methyl 6-aminonicotinate is by reacting nicotinic acid (nicotinic acid) and methanol under acidic conditions. The specific synthetic route is to acetalize nicotinic acid with methanol in the presence of an acidic catalyst (such as sulfuric acid or hydrochloric acid) to produce the corresponding nicotinyl aldehyde, which is then reacted with ammonia to produce Methyl 6-aminonicotinate.
In terms of safety, Methyl 6-aminonicotinate, as a chemical substance, has certain toxicity and needs to be properly handled and used. During use, pay attention to prevent contact with skin, eyes and respiratory tract. Therefore, when used in laboratory or industrial production, appropriate protective measures should be taken, such as wearing gloves, glasses and masks. In addition, it should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
During the use of any chemical substance, it is necessary to follow safe operating procedures and store, handle and dispose of it in accordance with relevant regulations. If you have any questions about the use of this compound or need further information, it is recommended to consult the relevant professional body or chemical expert.
Last Update:2024-04-09 20:52:54